PEA

Not the little green veg you have with lamb, or the pea fiber.

PEA in the supplement world is the shorten version of Palmitoylethanolamide. It is an endcannabinoid-like lipid. A fatty acid. This is a little different than normal fatty acids as it is amide-containing fatty acids which the cannabinoids are directly involved in nerve communication.

PEA has recently-discovered molecules which are called “neuroactive lipids

It is naturally in every body including our pets and even some plants. It naturally increases and decrease in the body as we need it for damaged- exposed cells.

It stops the activity of pro-inflammatory genes and many inflammatory substances. It helps brake down natural cannabinoid anandamide which increases the level of calming anandamide in the body.

Anandamide takes it name from joy, bliss, delight. It engages the bodiy's endcannabinoid system. This binding to the same cannabinoid receptors the THC found in Cannabis acts on.

Pea has a long history of safe use and regulatory approval from many countries. The benefits without the side effects.

It's found in the tissue of many animals and in plants such as the cacao tree.

This process helps combat pain and increases relaxation.

Pea is approved by the FDA as a food not used to treat or prevent illness. In Europe especailly countries like Itlay, Germany and Spain, it was promoted as a dietary food supplement for special medical purposes in 2017 but has reclassified as a food supplement. More studies are required,especially in humans, but saying this it is a supplement that has been studied and documented in animals to help a range of symtoms. It has been suggested to use for 3 months then given a rest from usage and start again . It is often good to give supplements a rest now and again. Have different ones layer the defence.

Any thing we can use instead of nsaids in ourself and our dogs is always worth reseaching. With so many dogs having issues with joints, eye disease and sezuires at younger ages now its worth looking at alternatives first.

Nsaids (non steroid prescribed and over the counter pain and anti inflammatory drugs) too many people just say take a nsaid for whatever the promblem is . Nsaids definnatley have there place but with care and knowledge as these drugs are always hard on the kidneys and can have side effects after long term use. Nsaids (non steroid pain and inflammation ) also arent always good and often over prescribed or suggested. The FDA in America say NSAIDs should be used cautiously in dogs with kidney, liver, heart, and digestive problems.

A natural alternative is always worth thinking about.

I started my Shar Pei on PEA a few years back. He gets Shar Pei fever which is a inflammatory disease and many get swollen hocks which can be very painfull. I found the PEA helps keep the fevers away, and helps reduce the swelling in the hocks. PEA takes about 2 weeks to work unlike pain meds that are straight away but one study found, in a study of sciatica pain in people, after 3 weeks it was found using a stronger dose gave 50% reduced pain which is something most pain killers can't achieve.

Animal studies have shown reduced nerve pain, reduced inflammation, reduced lung damage. Better pain and inflammation care in arthritis. More studies are hopefull in people. The interesting thing about PEA is it shows no real side effects or long term effects or medication interactions of course this is still being studied so they suggest not to give it to the very young or pregnant or breast feeding. otherwise it has been shown to be safe.

It is a helpfull tool in other areas in humans and pets

It is said to be benefifical for neurodegenerate disease. It helps brain cells survive in strokes and other brain issues and lowers inflammation. It is being looked at when helping people with Parkinson's disease. It could help prevent this by reducing damage in the brain and protecting dopamine neurons which causes Parkinsons. Brain health is important and this could help behaviour,cognition, mood and seizure risk. There are a few studies in rats. where PEA relieves sezuires and shortens duration in rats. Any tests on humans is yet to be done.

PEA reduces eye damage . In clinicial trails people with glaucoma had improved vision and reduced eye pressure over 6 months with no side effects. It also shows a reduction in eye pressure after laser surgery.

It has helped people with depression, symptoms of multiple sclerosis, fighting the common cold. It actually has been shown to help you stop catching a cold . It helps the heart it helps lower blood pressure and lowered inflammatory cytokine levels . It helps the gut . Some scientists think it may be a histamine release blocker. In animal studies PEA improved eczema and skin allergies with lowering mass cell activation which also helps prevent mass cell cancers. It smooths the skin reducing skin inflammation and itching and strongly diminishes allergic responses.

We and our pets produce Palmitoylethanolamide naturally in our bodies. It is also found in foods, the highest is soy lecithins, soybeans ,egg yolks and peanuts. Much of the orginal research on PEA was published in Italian so it started as a european secret as such. There is a study by BMC veterinary reseach that a formulation of PEA and Quercetin (quercetin being a benefical supplement in allergies amongst other benefits used in dogs and humans) deceases inflammatation and relieves the pain in osteoarthric pain.

These results showing a comparable and somewhat better result than those of meloxicam. study

The best PEA to buy is Ultra Micronized PEA which is better absorbed and with no fillers, sugers or sweeteners. Always read the label and know the products as these arent always listed. If unsure buy safe for animal versions from a quality trusted company. I have used a human supplement but with lots of reseach into the supplement and company and a dog labeled product. I have seen this for made for dogs and horses.

Do not confuse palmitoylethanolamide with phenethylamine these are not the same but can both be called PEA. Phenethylamine is similar to the drug amphetamine with simular side effects and IS NOT palmitoylethanolamide.

This is an information blog and is not intended to diagnose, treat, cure or prevent any disease.”

https://www.dvm360.com/view/new-human-grade-palmitoylethanolamide-supplement-for-dogs-and-cats

links on PEA and eye health, Judy Morgan the human grade PEA for cats and Dogs does PEA have health benefits Efficacy of ultra-micronized palmitoylethanolamide in canine atopic dermatitis: an open-label multi-centre study National libery of medicne